Novel Staining Approach: Assessing the Comparative Efficacy of BlueStain® in Diagnostic Cytopathology
Anfitriã: Françoise Kleinsorgen (Doutoranda em Ciências Biomédicas no IUCS-CESPU)
Palestrante: Paulo Melo
Afiliação: IUCS- Cespu, Cespu Diagnóstico, Unipro
15 de maio | 12h
Campus Universitário de Gandra | Ed. 2 | Sala 2148
ENTRADA LIVRE
Resumo:
In the evolving field of cytopathology, innovation is essential for improving diagnostic efficiency, accuracy, and sustainability. Traditional staining techniques, though reliable, often involve high costs, extended processing times, and environmental concerns. This study presents BlueStain®, a novel single-reagent stain developed to address these issues while maintaining diagnostic quality. BlueStain® was assessed through a structured evaluation process to verify its scientific validity, analytical, and clinical performance. It was compared with established cytological stains such as Papanicolaou, Diff-Quik, and Giemsa across various sample types, including thyroid fine needle aspirations, serous effusions, and cervical smears. Results showed that BlueStain® provided clear, high-quality slides suitable for accurate diagnostic interpretation, particularly in rapid on-site evaluations. Beyond diagnostic performance, BlueStain® offers environmental and economic benefits due to its single-reagent format, which reduces hazardous waste and lowers costs associated with multi-step staining procedures. In conclusion, BlueStain® emerges as a viable alternative to conventional staining methods, offering a balanced approach to diagnostic quality, cost-effectiveness, and environmental sustainability. Further clinical validation and expansion into other areas of cytopathology and histopathology are recommended.
Nota Biográfica:
Paula Melo holds a PhD in Pathology and Molecular Genetics from the University of Porto. She graduated in Pathological Anatomy from the Polytechnic Institute of Health North in 2008. In 2016, she completed an executive postgraduate program after founding a startup that developed an innovative medical device, which earned several awards for entrepreneurship and innovation. Since then, she has been actively involved in various research projects and business development initiatives in the healthcare sector, including the establishment of spinoff companies at CESPU. Paula has contributed to numerous research and development projects as a researcher and co-author of international patent applications. Additionally, she has been teaching Human Anatomy and Histology in various undergraduate programs at the Cooperative of Polytechnic and University Higher Education (CESPU) since 2009.
