Bruno Sarmento (Docente do Curso de Mestrado Integrado em Ciências Farmacêuticas da CESPU - Instituto Universitário de Ciências da Saúde), é o autor da 1ª edição do livro científico intitulado:
Concepts and Models for Drug Permeability Studies
Cell and Tissue based In Vitro Culture Models
“This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route”.
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